Webinar Description:

In this webinar, we will discuss design and development of translational in vitro models with better validity for chronic pain drug discovery. We will discuss how to select between animal and human models for your discovery research and how to bridge between rodent-based and human neuronal assays as well as opportunities and limitations of human models from iPS cells and native human nerve tissue.  We will also provide our view on how to address lack of efficacy as early as possible in the drug discovery path by sharing case studies from our lab and from the literature.

Finally, we will share our vision on how to develop “disease in a dish” microfluidic co-culture models to study the interaction between neuronal cells and target organs such as bone and skin in chronic pain. Applying optical electrophysiology in combination with a novel microfluidics platform, we aim to create unique high capacity in vitro assays as means to aid in the understanding of mechanisms of peripheral pain.

Wednesday, November 13 @ 5 pm CET / 11 am EST / 8 am PST

Click here for more information and to register for the event.

 

The Neuroscience 2019 meeeting takes place in Chicago on October 19-23. We invite you to reach out to set up a meeting or to meet with the Cellectricon team in stand 374 in the exhibit hall.

During the conference, we will present several posters covering some of the exciting research that we, and our partners, are conducting.

Recommended posters:

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In August, Cellectricon welcomed our new coworker Lydia Moll. Lydia will carry out her PhD project at the company over the next four years. The project is part of BonePain II, a European Innovative Training Network committed to promote research, innovation and education within bone pain. The network brings together academic and industrial partners to provide early stage researchers with outstanding training and secondments. The network had an official kick-off on September 19-20 at the Royal Veterinary College in London (UK).

Lydia received her bachelor’s degree in Molecular and Technical Medicine from Furtwangen University (Germany) and graduated with an MSc in Cell and Tissue Engineering at Keele University (UK). Her research projects focused on musculoskeletal diseases and stem cell differentiation. For example, she worked on the establishment of an intervertebral disc organ culture model as well as the evaluation of hydrogel environments on the cartilaginous differentiation of pluripotent stem cells.

During her PhD project at Cellectricon Lydia will work to develop “disease in a dish” microfluidic co-culture models to study bone and neuronal cell interactions and their possible contributions to bone pain. A special focus will be on antibody-driven pain in arthritis, the mechanisms, and possible treatment options for arthritis. The project will also include secondments in the molecular pain research group of Professor Camilla Svensson at Karolinska Institutet, Stockholm (Sweden) with the ambition to translate the in vitro findings to the in vivo setting.

 

BonePain II training network

 

The first annual meeting of the BonePain II network at the Royal Veterinary University in London (UK) brought together the Marie-Curie fellowship PhD students, recruited from all over the world, as well as their supervisors and industrial collaborators. The meeting gave the participants opportunity to present their research topic, exchanging knowledge, and building networks for the future. The conference program was completed by courses in animal pain measurement and workshops for cross-cultural management skills. The Cellectricon team is looking forward to welcoming students from Copenhagen, Stockholm, Porto, and Utrecht for secondments at Cellectricon during the next years, and the opportunity to give them insights in how to apply our technologies in chronic pain research as well as experience from research in an industrial setting.

The conference will focus on discussing the latest technologies in the preclinical, translational neuroscience space and also drawing the attention of the audience towards new innovations happening in translational neuroscience imaging. The conference further aims to bring in the experts from academia and industry together to discuss how to create new, more effective translational neuroscience drawing on novel technology and recent discoveries.

Paul Karila, CSO & Director, chronic pain research, will give a presentation on Oct 3 at 10.10 am titled:

How can we achieve better translation from in vitro to the clinic in neuroscience?

The talk will cover:

  • Bridging from rodent-based to human neuronal assays: How can we accelerate building in vitro models with better translational validity?
  • Opportunities and limitations of human models from iPS cells and native human nerve tissue.
  • Innovative co-culture assays for combined functional and morphological screening.

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Neuroscience in Discovery & Development Congress takes place in Berlin, Germany on June 11-12. The meeting is part of Oxford Global’s R&D Europe Series and is co-located with the 20th Annual Drug Discovery Summit. The Congress will bring together key experts for presentations and case studies on the latest discoveries in CNS, along with patient stratification and biomarker development for neuroscience.

If you are interested in learning more about Cellectricon’s drug discovery services you are very welcome to reach out and schedule a meeting with us.

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NDD Europe 2019 took place in Paris, France on May 22-23. The meeting was focused on neurodegenerative diseases and provided members of the drug development community with an opportunity to discuss how to overcome the translational challenges in the development of clinically disease-modifying therapeutics.

If you are interested in learning more about Cellectricon’s drug discovery services you are very welcome to reach out and schedule a meeting with us.

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The 7th International Congress on Neuropathic Pain (NeuPSIG 2019) took place in London, UK on May 9-11, 2019. It is an international forum that provides the latest research and developments in understanding the mechanisms, assessment, prevention and treatment of neuropathic pain. This years’ meeting included two themes; diabetic neuropathic pain & chemotherapy-induced peripheral neuropathic pain.

If you did not attend the meeting, or missed the poster presentations, you are very welcome to reach out to learn more.

Recommended posters:

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